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Newly Announced Motorola Defy is Rugged and Runs Android 2.1

Newly Announced Motorola Defy is Rugged and Runs Android 2.1

Who said rugged meant a phone had to actually look like a piece of military equipment? With the announcement of the Motorola Defy, Moto brings their second Android handset specced out to resist the elements and keep chugging under even the most hostile conditions. Taking a page from the Motoro

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Science Team Make Gut Bacteria Do Math: Living Computers On Way? [Slimy

Science Team Make Gut Bacteria Do Math: Living Computers On Way? [Slimy

Computers made by this method would be superfast no doubt replacing electrons with bateria at a microscopic level good small, efficient, but god, imagine when bateria & living cells form computers, medical companies will be having a good time producing "antibiotics" for feeding your computer too

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Putting Multiple Credit Card Accounts On the Same Plastic

Putting Multiple Credit Card Accounts On the Same Plastic

The worst part about getting your credit card declined? Reaching back into your wallet to find one that works. Embarrassing! The Dynamics Card 2.0 MultiAccount feature solves that by putting two different accounts on the same piece of plastic. Card 2.0, shown off today for the first time, feature

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Intel's 6-Core Gulftown Gets Tested, Blows Us Away

Intel's 6-Core Gulftown Gets Tested, Blows Us Away

Six cores. That's how many are in Intel's ridiculous new Core i7-980x. MaximumPC takes us deep inside the world's fastest CPU, with full, mind-searing benchmarks. Meet the world's fastest CPU. OK, so we just gave away the big reveal to our report before you even flipped one page, and without s

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Broadcom Launches 802.11n Wi-Fi Chip For Cellphones

Broadcom Launches 802.11n Wi-Fi Chip For Cellphones

The new chip, which also integrates Bluetooth and FM radios, can grab 802.11n data at speeds of up to 50Mbps, and Broadcom claims it can do it all without totally devastating your battery. While mobile browsers are far from fast enough to handle data coming in at draft-N speeds, this does op

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Nokia PC Suite 7.0 Release 8.2 Final

Nokia PC Suite 7.0 Release 8.2 Final

Nokia PC Suite is a package of Windows-based PC applications developed especially for use with Nokia phones. Depending on your phone model, Nokia PC Suite lets you edit, synchronize and back up many of your phone's files on a compatible PC through a cable or wireless connection. Key features

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Urine a candidate for energy independence

Urine a candidate for energy independence

We thought we were supposed to have fusion-power for our DeLorean by now but it perhaps urine-power is just around the corner instead. [Gerardine Botte] has been working on creating hydrogen from urine, the world’s most abundant waste product. The voltage needed to break apart the urea atoms

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Opera 9.6 Faster, Stronger, Available Now

Opera 9.6 Faster, Stronger, Available Now

Opera just popped out the latest version of their desktop browser, 9.6. Besides being just plain faster, it adds feature improvements all around, like a new low-bandwidth mode in the built-in email client, expanded syncing (speed dial, search engines and notes), and RSS feed previews, so you c

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Creme That Egg: Rube Goldberg Machine Destroys Easter In 8,000 Easy Steps

[youtube]http://www.youtube.com/watch?v=vrCb_fNmSTA[/youtube] I have to admit, this Rube Goldberg machine is pretty friggn' ingenious—even if it does result in a the gruesome death of a delicious Cadbury Egg. [Telegraph via Jezebel]

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DNA Logic Gates Could Bring Injectable Biocomputers

DNA Logic Gates Could Bring Injectable  Biocomputers

DNA-based logic gates that could carry out calculations inside the body have been constructed for the first time. The work brings the prospect of injectable biocomputers programmed to target diseases as they arise.

“The biocomputer would sense biomarkers and immediately react by releasing counter-agents for the disease,” says Itamar Willner of the Hebrew University of Jerusalem, Israel, who led the work.

DNA Logic Gates Could Bring Injectable  Biocomputers

The new logic gates are formed from short strands of DNA and their complementary strands, which in conjunction with some simple molecular machinery mimic their electronic equivalent. Two strands act as the input: each represents a 1 when present or a 0 when absent. The response to their presence or absence represents the output, which can also be a 1 or 0.

Take the “exclusive OR” or XOR logic gate. It produces an output when either of the two inputs is present but not when both are present or both are absent. To put the DNA version to the test, Willner and his team added molecules to both the complementary strands that caused them to fluoresce when each was present in isolation, representing a logical 1 as the output. But when both were present, the complementary strands combined and quenched the fluorescence, representing a 0 output.

Simultaneous calculations

One of DNA computing’s advantages is that it allows calculations to be carried out in parallel, if different types of logic gates are represented by different ingredients. The team tested this process by tossing the XOR ingredients into a test tube, along with those for two other gates, to produce the first few steps involved in binary addition and subtraction.

The team was also able to create logic gates that calculate in sequence. The trick here is to make the output from the first gate a new DNA string that can be used as the input for a second gate and so on. Such “cascading gates” allow for more complex calculations: the entire set of steps required for addition and subtraction, for example, or to deliver a multi-step drug treatment.

Previous DNA-based computers tended to slow down at each step as the DNA strands were used only once, and so became depleted with time. One significant advance claimed by Willner and his team is that their DNA strands reform after each step, allowing long sequences of calculations to be carried out easily for the first time.

Even a single logic gate could have useful applications, Willner says. His group built and tested a gate designed to reduce the activity of the blood-clotting enzyme thrombin, which can lead to brain damage following a head injury. The gate acts as a switch that is triggered by the presence of thrombin. Part of the gate consists of a DNA strand connected to a molecule that binds to thrombin. If thrombin is present, this molecule is released, otherwise it stays bound and inert. Such a smart drug could be injected into the bloodstream in advance and would only switch on when needed (Nature , DOI: 10.1038/nnano.2010.88).

Another problem with earlier DNA computers is that they use enzymes to manipulate the DNA, and so function only in certain environments that cannot easily be reproduced inside the body. Willner’s team use DNA-like molecules to do this job.

“Being enzyme-free, it has potential in future diagnostic and medical applications,” says Benny Gil of the Weizmann Institute of Science in Rehovot, Israel. He is impressed with the new gate system but recognises that it will take years of research and development to bring “smart drugs” to medicine.

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